Several basic science studies suggest that PRP treatment can improve healing in soft tissue and bone. For example, increased numbers of cells and improved tendon strength have been noted in Achilles tendon injuries, and improved muscle regeneration has been shown in gastrocnemius (calf) muscle injuries. It is considered a relatively low-risk treatment with the potential to improve or speed healing.
In a small study involving knee osteoarthritis, PRP treatment was shown to be more effective than hyaluronic acid treatment. PRP has also resulted in positive or similar results when used in the treatment of rotator cuff tears and medial collateral ligament (MCL) injuries in the knee.
Because PRP is given in the hopes of optimizing the initial inflammatory response of healing, anti-inflammatory medications should likely be stopped at the time of PRP treatment.
Platelet-rich plasma (PRP) comes from a patient's own blood. PRP is a concentrated source of growth factors and cellular signaling factors that play a significant role in the biology of healing. Basic science studies show that PRP treatment may improve healing in many tissues.